Toray Japan has announced the development of a new fiber sorbent that can be used to purify blood. It can selectively destroy cells by controlling the surface morphology and chemical structure of the "island-type" composite fiber obtained by synthetic fiber spinning technology. Biological targets such as proteins. This new fiber sorbent offers higher performance and safety than traditional fiber sorbents. Toray will begin clinical trials of the fiber in FY 2019.
This fiber adsorbent developed by Toray can selectively destroy cells (activated white blood cells) and proteins (cytokines) that induce inflammation without affecting cells and proteins that maintain human health. The types of cells and proteins that are eliminated can be independently controlled by changing the surface morphology of the fibers or by chemical modification. Toray uses its new spinning technology, NANODESIGN®, to successfully control the high-activity polymers that are susceptible to structural and chemical modifications at the nanoscale and the arrangement of stable polymer molecules that maintain fiber strength.
In 1994, Toray developed the world's first blood purification equipment, TORAYMYXIN®, which eliminates endotoxin cells that induce septic shock, mainly in emergency centers and intensive care units. TORAYMYXIN® uses an adsorbent to destroy this cytotoxin called endotoxin. However, numerous user feedbacks indicate that not only products that can remove endotoxin cells, but also purification column products that can eliminate more pathogens are needed. In the end, more than 20 years of research and development achievements have made this fiber sorbent product launched by Toray.
The circulating blood passes through a purification column containing an adsorbent, and the highly selective adsorption adsorbent can effectively eliminate pathogenic substances related to sepsis, acute lung injury and cancer, which can cause serious inflammatory reactions, without reacting with essential protein. . Toray will conduct animal testing of new technologies in conjunction with leading universities in Japan and internationally, and consider starting commercial operations to provide new treatments for countless patients.
In the mid-term management plan "AP-G 2019", Toray said it is working on the Life Innovation Business Development (LI) project, which aims to improve health care, reduce the burden on medical institutions and expand health-related businesses. The project plans to achieve sales revenue of 300 billion yen by the medical and health business segment by 2020.
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